DS-1040 Tosylate |
カタログ番号GC32492 |
DS-1040 Tosylate は、活性化トロンビン活性化線維素溶解阻害剤 (TAFIa) の選択的経口活性阻害剤であり、ヒトおよびラットの TAFIa に対する IC50 は 5.92 nM および 8.01 nM です。
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Cas No.: 1335138-89-0
Sample solution is provided at 25 µL, 10mM.
DS-1040 Tosylate is an inhibitor of the activated thrombin-activatable fibrinolysis inhibitor (TAFIa), used for the treatment of acute ischemic stroke (AIS).
[1]. Zhou J, et al. A first-in-human study of DS-1040, an inhibitor of the activated form of thrombin-activatable fibrinolysis inhibitor, in healthy subjects. J Thromb Haemost. 2017 May;15(5):961-971.
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