E 5555 hydrobromide - AtopA1ar hydrobromide |
カタログ番号GB40189 |
強力で経口的に作用するトロンビン受容体(またはプロテアーゼ活性化受容体1、PAR1)拮抗剤(IC50:19 nM)。E5555は、トロンビンおよびTRAPによって誘発されるヒト血小板凝集の阻害効果があり、それぞれのIC50値は64および31nMです。
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Cas No.: 474550-69-1
Sample solution is provided at 25 µL, 10mM.
Potent and orally active thrombin receptor (or protease-activated receptor 1, PAR1) antagonist (IC50: 19 nM); E5555 showed potent inhibitory effects on human platelet aggregation induced by thrombin and TRAP with IC50 values of 64 and 31nM, respectively
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