Ebelactone A (Synonyms: (-)-Ebelactone A, NSC 335650) |
| カタログ番号GC40277 |
イベラクトンAは、土壌アクチノマイセスの培養株から最初に単離されたβ-ラクトン酵素阻害剤です。
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Cas No.: 76808-16-7
Sample solution is provided at 25 µL, 10mM.
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Ebelactone A is a β-lactone enzyme inhibitor that was first isolated from a cultured strain of soil actinomycetes. It can inhibit esterases, lipases, and N-formylmethionine aminopeptidases (IC50s = 0.056, 0.003, and 0.08 µg/ml, respectively) found on cell surfaces, which has been shown to stimulate host defense in immune cells. Ebelactone A is also reported to inhibit cutinases produced by fungal pathogens, thus demonstrating a plant-protective function.
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