Eicosanedioic acid |
| カタログ番号GC66214 |
エイコサン二酸は、抗体薬物複合体 (ADC) の合成に使用される非切断型 ADC リンカーです。エイコサン二酸は、合成に使用できるアルキル鎖ベースの PROTAC リンカーでもあります。
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Cas No.: 2424-92-2
Sample solution is provided at 25 µL, 10mM.
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Eicosanedioic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Eicosanedioic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2].
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