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ERRγ agonist-1

カタログ番号GC70943

ERRγ agonist-1は要りγ作動薬で誤るな

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ERRγ agonist-1 化学構造

サイズ 価格 在庫数 個数
10mM (in 1mL DMSO)
$246.00
在庫あり
5 mg
$223.00
在庫あり
10 mg
$358.00
在庫あり
25 mg
$716.00
在庫あり

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
ERRγ agonist-1 is a potent ERRγ agonist. ERRγ agonist-1 increases transcriptional activities of ERRγ. ERRγ agonist-1 has the potential for the research of neuropsychological disorders.

ERRγ agonist-1 (compound 5d) (5 µM; 3 days) significantly increases the expression of tyrosine hydroxylase (TH) and dopamine transporter (DAT), DAergic neuronal phenotypes (dopaminergic neuronal phenotype) in neuroblastoma SH-SY5Y cells[1].
ERRγ agonist-1 (5 µM; 3 days) induces DAergic neuronal phenotypes via the ERRγ-mediated up-regulation of CREB-signaling pathway[1].

References:
[1]. Kim T, et al. Discovery of new ERRγ agonists regulating dopaminergic neuronal phenotype in SH-SY5Y cells. Bioorg Chem. 2022; 122:105716.

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