Euphol Acetate |
| カタログ番号GC46145 |
酢酸ユーフォルビアは、ユーフォルビア ブロテリから分離できるトリテルペンです。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 13879-04-4
Sample solution is provided at 25 µL, 10mM.
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Euphol acetate is a triterpenoid that has been found in Euphorbia species and has diverse biological activities.1,2,3 It reduces sodium fluorescein uptake by CHO cells expressing organic anion-transporting polypeptide 1B1 (OATP1B1) and OATP1B3 to 29.2 and 40.2% of controls, respectively, when used at a concentration of 10 μM.3 Euphol acetate (50 and 100 μg/ml) induces mortality in 40% of B. glabrata snails.2
|1. De Pascual Teresa, J., Urones, J.G., Marcos, I.S., et al. Triterpenes from Euphorbia broteri. Phytochemistry 26(6), 1767-1776 (1987).|2. Mata, R.C.S., de Mendon•a, I.M.D., Vieira, L., et al. Molluscicidal activity of compounds isolated from Euphorbia conspicua N. E. Br. J. Braz. Chem. Soc. 22(10), 1880-1887 (2011).|3. De Bruyn, T., van Westen, G.J.P., Ijzerman, A.P., et al. Structure-based identification of OATP1B1/3 inhibitors. Mol. Pharmacol. 83(6), 1257-1267 (2013).
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