Ezetimibe-d4-1 (Synonyms: SCH 58235-d4-1) |
| カタログ番号GC66354 |
Ezetimibe-d4 は、Ezetimibe と標識された重水素です。エゼチミベ (SCH 58235) は強力なコレステロール吸収阻害剤です。エゼチミベはニーマン・ピック C1-like1 (NPC1L1) 阻害剤であり、強力な Nrf2 活性化剤です。
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Cas No.: 1093659-89-2
Sample solution is provided at 25 µL, 10mM.
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Ezetimibe-d4 is deuterium labeled Ezetimibe. Ezetimibe (SCH 58235) is a potent cholesterol absorption inhibitor. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator.
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
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