F9170 (trifluoroacetate salt) |
カタログ番号GC91466 |
F9170は、HIV-1エンベロープグリコ蛋白質のアミノ酸789〜803に対応する抗ウイルスペプチドです。
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Sample solution is provided at 25 µL, 10mM.
F9170 is an antiviral peptide corresponding to amino acids 789-803 of the HIV-1 envelope glycoprotein.1 It binds to the LLP1 domain within the HIV-1 envelope protein cytoplasmic tail and inhibits HIV-1 IIIB infection of MT-2 cells (EC50 = 0.19 µM). F9170 (3 mg/kg) reduces plasma viral load in a rhesus macaque model of simian HIV (SHIV) infection.
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