Ferroprotoporphyrin (Synonyms: Ferrous Protoporphyrin IX, Heme, Heme b, Heme Fe(II) Complex, Iron Protoporphyrin IX, NSC 267100, Protoporphyrin IX Iron Complex) |
| カタログ番号GC49230 |
第一鉄とポルフィリンの複合体であるフェロプロトポルフィリンは、ラット肝臓の脂肪酸結合タンパク質に結合する脂肪酸のアイソステリック阻害剤です。
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Cas No.: 14875-96-8
Sample solution is provided at 25 µL, 10mM.
Ferroprotoporphyrin is an iron-containing cofactor.1,2 It is involved in several biological processes such as the transport or storage of oxygen by hemoglobin or myoglobin, respectively, electron transfer by cytochrome b5, and oxidation of xenobiotics or endogenous substrates by cytochrome P450s (CYPs).
1.Shimizu, T., Lengalova, A., MartÍnek, V., et al.Heme: Emergent roles of heme in signal transduction, functional regulation and as catalytic centresChem. Soc. Rev.48(24)5624-5657(2019) 2.Schneider, S., Marles-Wright, J., Sharp, K.H., et al.Diversity and conservation of interactions for binding heme in b-type heme proteinsNat. Prod. Rep.24(3)621-630(2007)
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