Fitusiran (Synonyms: ALN-AT3SC; SAR439774) |
| カタログ番号GC65060 |
低分子干渉 RNA である Fitusiran (ALN-AT3SC) は、特にアンチトロンビン (AT) メッセンジャー RNA を標的として、肝臓での AT の産生を低下させます。
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Cas No.: 1499251-18-1
Sample solution is provided at 25 µL, 10mM.
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Fitusiran (ALN-AT3SC), an small interfering RNA, specifically targets antithrombin (AT) messenger RNA to lower production of AT in the liver. Fitusiran increases thrombin generation and has the potential for the research of the hemophilia[1].
[1]. Pasi KJ, et al. Targeting of antithrombin in hemophilia A or B with investigational siRNA therapeutic fitusiran-Results of the phase 1 inhibitor cohort. J Thromb Haemost. 2021;19(6):1436-1446.
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