Flavokawain A (Synonyms: Flavokavain A, 4-methoxy Flavokawain B) |
| カタログ番号GC60845 |
有望な抗発がん剤であるフラボカワイン A は、抗腫瘍活性を持つカバ抽出物からのカルコンです。 Flavokawain A は、Bax タンパク質依存性およびミトコンドリア依存性アポトーシス経路の関与により、細胞アポトーシスを誘導します。フラボカイン A は、膀胱癌の研究の可能性を秘めています。
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Cas No.: 3420-72-2
Sample solution is provided at 25 µL, 10mM.
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Flavokawain A, a proming anticarcinogenic agent, is a chalcone from kava extract with anti-tumor activity. Flavokawain A induces cell apoptosis by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway. Flavokawain A has the potential for the study of bladder cancer[1].
[1]. Xiaolin Zi, et al. Flavokawain A, a novel chalcone from kava extract, induces apoptosis in bladder cancer cells by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway and suppresses tumor growth in mice. Cancer Res. 2005 Apr 15;65(8):3479-86.
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