Fosravuconazole (BMS-379224) (Synonyms: BMS-379224; E-1224) |
| カタログ番号GC33996 |
ラブコナゾールのプロドラッグであるホスラブコナゾール (BMS-379224) (BMS-379224) は、経口活性のある広域スペクトル抗真菌剤です。
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Cas No.: 351227-64-0
Sample solution is provided at 25 µL, 10mM.
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Fosravuconazole is a prodrug of ravuconazole, with antifungal activity.
Fosravuconazole (BMS-379224) is a prodrug of ravuconazole, with antifungal activity[1].
Fosravuconazole (BMS-379224) is rapidly conversed to ravuconazole upon iv administration to rats. Fosravuconazole shows comparable efficacy at inhibiting C. albicans infection model in mice as orally administered ravuconazole[1].
[1]. Ueda Y, et al. Phosphonooxymethyl prodrugs of the broad spectrum antifungal azole, ravuconazole: synthesis and biological properties. Bioorg Med Chem Lett. 2003 Nov 3;13(21):3669-72.
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