FR900098 (sodium salt) |
| カタログ番号GC43699 |
FR900098は、抗マラリア活性を持つフォスミドマイシンの誘導体です（HB3、A2、およびDd2 Pに対するIC50はそれぞれ170、170、および90 nM）。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 73226-73-0
Sample solution is provided at 25 µL, 10mM.
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FR900098 is a derivative of fosmidomycin that has antimalarial activity (IC50s = 170, 170, and 90 nM for HB3, A2, and Dd2 P. falciparum strains, respectively). FR900098 inhibits DOXP reductoisomerase, a key enzyme in the non-mevalonate pathway of isoprenoid biosynthesis, in vitro in a dose-dependent manner. FR900098 (>10 mg/kg, i.p.) eradicated P. vinckei parasites within four days in mice.
Average Rating: 5 (Based on Reviews and 17 reference(s) in Google Scholar.)
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