(His³²,Leu³⁴)-Neuropeptide Y (32-36) |
カタログ番号GA20219 |
非活性のNPYカルボキシ末端ペンタペプチド(IC?? > 100 µM)は、スレオニンをヒスチジンに、グルタミンをロイシンに置換することで修飾されました。その結果得られたペプチドは、ラット脳受容体に対する親和性が劇的に改善されました(IC?? = 0.45 µM)。
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Cas No.: 168916-68-5
Sample solution is provided at 25 µL, 10mM.
The inactive NPY carboxy-terminal pentapeptide (IC50 > 100 µM) was modified by replacing threonine with histidine and glutamine with leucine. The resulting peptide had a dramatically improved affinity (IC50 = 0.45 µM) for the rat brain receptor
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(Based on Reviews and 26 reference(s) in Google Scholar.)Review for (His³²,Leu³⁴)-Neuropeptide Y (32-36)
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