Cyclo(-Gly-Arg-Gly-Asp-Ser-Pro-Ala) |
| カタログ番号GA21324 |
RGDを含むペプチドであるc(GRGDSPA)が、刺激された血小板におけるフィブロネクチンの結合をIC??= 0.223 µMで阻害することが示されています。c(GRGDSPA)はまた、トロンビン誘発性血小板凝集をIC??= 32 µMで阻害しますが、この点では天然のフィブロネクチンよりも効力が低いです。
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Cas No.: 128857-77-2
Sample solution is provided at 25 µL, 10mM.
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It has been demonstrated that the RGD-containing peptide, c(GRGDSPA), inhibited the binding of fibronectin to stimulated platelets with IC50= 0.223 µM. c(GRGDSPA) also blocked thrombin-induced platelet aggregation with IC50= 32 µM, but was less
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