H-Cys-Arg-Gly-Asp-Phe-Pro-Ala-Ser-Ser-Cys-OH |
カタログ番号GA22168 |
CRGDFPASSCは、血小板表面のフィブリノーゲン受容体に結合する環状RGD含有デカペプチドです。このアナログは、位置5のSerがPheに置換されたものであり、血小板凝集阻害剤としてCRGDSPASSCよりも3倍活性が高いことが発見されました(IC?? = 2.5 µM)。
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Cas No.: 166184-23-2
Sample solution is provided at 25 µL, 10mM.
CRGDFPASSC is a cyclic RGD-containing decapeptide which binds to the fibrinogen receptor on the platelet surface. This analog with Phe substituted for Ser at position 5 was found to be 3 times more active (IC50 = 2.5 µM) as a platelet aggregation i
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