H-p-Chloro-Phe-D-Cys-β-(3-pyridyl)-Ala-D-Trp-Lys-Val-Cys-p-chloro-Phe-NH₂ |
カタログ番号GA22777 |
ウロテンシンII受容体拮抗剤であるSB-710411(Cpa-D-Cys-Pal-D-Trp-Lys-Val-Cys-Cpa-amide)は、ウロテンシン受容体の結合/機能を阻害し、またラット孤立した大動脈においてエンドセリン1誘発性収縮を増強することが示されました。Liuらは、SB-710411がCCL4肝硬変ラットにおける線維化を停止させることを観察しました。
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Cas No.: 209006-05-3
Sample solution is provided at 25 µL, 10mM.
The urotensin ll receptor antagonist SB-710411 (Cpa-D-Cys-Pal-D-Trp-Lys-Val-Cys-Cpa-amide) showed inhibition of the urotensin receptor binding / function and also potentiated endothelin-1 induced contraction in the rat isolated aorta. Liu et al. observ
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