H-Tyr-Ile-Gly-Ser-Arg-OH |
カタログ番号GA22975 |
ラミニンB1鎖のドメインIII内に位置するペンタペプチドYIGSRは、ラミニンにおける主要な受容体結合部位を表します。細胞表面受容体と競合することで、この短いペプチドは基底膜への細胞付着を阻害し、腫瘍転移の形成を防止することができます。YIGSRはまた、腫瘍細胞の移動を促進し、さらに様々な上皮細胞がラミニンに対して接着するための媒介物質でもあります。
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Cas No.: 110590-64-2
Sample solution is provided at 25 µL, 10mM.
The pentapeptide YIGSR located within domain III of the laminin B1 chain, represents a major receptor binding site in laminin. By competing with laminin for the cell surface receptor, the short peptide is able to inhibit cell attachment to basement mem
Average Rating: 5
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