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Z-Phe-His-Leu-OH

カタログ番号GA23899

アンジオテンシンI変換酵素の基質。ACEによるZ-FHLの切断により、His-Leu(G-2310)が生成され、o-フタルアルデヒドと蛍光付加物を生成することで定量化できます。

Products are for research use only. Not for human use. We do not sell to patients.

Z-Phe-His-Leu-OH 化学構造

Cas No.: 28458-19-7

サイズ 価格 在庫数 個数
250mg
$357.00
在庫あり
1g
$872.00
在庫あり

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Sample solution is provided at 25 µL, 10mM.

Description of Z-Phe-His-Leu-OH

Substrate for angiotensin I-converting enzyme. Cleavage of Z-FHL by ACE yields His-Leu (G-2310), which can be quantified by generating a fluorescent adduct with o-phthalaldehyde.

Chemical Properties of Z-Phe-His-Leu-OH

Cas No. 28458-19-7 SDF
Formula C29H35N5O6 M.Wt 549.63
溶解度 Soluble in DMSO Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Z-Phe-His-Leu-OH

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 1.8194 mL 9.097 mL 18.1941 mL
5 mM 0.3639 mL 1.8194 mL 3.6388 mL
10 mM 0.1819 mL 0.9097 mL 1.8194 mL
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**ストックソリューションを準備する際には、常にバイアルラベルおよび MSDS/CoA(オンラインで利用可能)で掲載された製品のロット固有分子量を使用してください。

計算

In vivo Formulation Calculator (Clear solution) of Z-Phe-His-Leu-OH

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

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Average Rating: 5 ★★★★★ (Based on Reviews and 26 reference(s) in Google Scholar.)

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