Amotosalen hydrochloride (Synonyms: S-59) |
| カタログ番号GC35326 |
アモトサレン塩酸塩 (S-59) は、光活性化された DNA、RNA 架橋ソラレン化合物で、病原体を中和するために使用されます 。
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Cas No.: 161262-45-9
Sample solution is provided at 25 µL, 10mM.
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Amotosalen hydrochloride (S-59) is a light-activated, DNA-, RNA-crosslinking psoralen compound, which is used to neutralise pathogens[1].
When activated by light, Amotosalen binds to the nucleic acid of the pathogen and prevents replication. Light-activated Amotosalen binds and permanently crosslinks DNA, preventing replication and thus stopping proliferation of donor T cells[1].
[1]. Amotosalen: Allogeneic Cellular Immunotherapies system, INTERCEPT Plasma System, INTERCEPT Platelet System, S 59. BioDrugs. 2003;17(1):66-8.
Average Rating: 5 (Based on Reviews and 23 reference(s) in Google Scholar.)
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