Aristolochic acid B (Synonyms: Aristolochic Acid II) |
カタログ番号GC35389 |
アリストロキア酸 B は、アリストロキア科の分類群に由来する天然物であるアリストロキア酸 (AA) の主要成分の 1 つです。アリストロキア酸は、強力な変異原物質および発がん物質であることが知られています。アリストロキア酸 B は、生体内でアリストロキア酸 A よりも発がんリスクが高いことを示します。
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Cas No.: 475-80-9
Sample solution is provided at 25 µL, 10mM.
Aristolochic acid B is one of the major components of Aristolochic acids (AA) which are natural products derived from taxa in the Aristolochiaceae. Aristolochic acid is known to be a potent mutagen and carcinogen. Aristolochic acid B showes more carcinogenic risk than Aristolochic acid A in vivo[1].
[1]. Xing G, et al. Comparison of the mutagenicity of aristolochic acid I and aristolochic acid II in the gpt delta transgenic mouse kidney. Mutat Res. 2012 Mar 18;743(1-2):52-8.
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