diABZI STING agonist-1 |
| カタログ番号GC35853 |
diABZI STING アゴニスト-1 は、選択的インターフェロン遺伝子刺激因子 (STING) 受容体アゴニストであり、EC50 はヒトおよびマウスでそれぞれ 130、186 nM です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2138299-33-7
Sample solution is provided at 25 µL, 10mM.
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diABZI STING agonist-1 is a selective stimulator of interferon genes (STING) receptor agonist. STING[1].
diABZI STING agonist-1 activates secretion of IFNβ, IL-6, TNF, and KC/GROα (also known as CXCL1) in wild-type but not Sting-/- mice, confirming that diABZI STING agonist-1 induces STING-dependent activation of type-I interferon and pro-inflammatory cytokines in vivo[1].
[1]. Ramanjulu JM, et al. Design of amidobenzimidazole STING receptor agonists with systemic activity. Nature. 2018 Nov 7.
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