Eprodisate |
| カタログ番号GC35999 |
エプロジセートは、アミロイド形成タンパク質とグリコサミノグリカン間の相互作用を妨害するように設計された新しい化合物であり、それによってアミロイド線維の重合と組織への線維の沈着を阻害します。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 21668-77-9
Sample solution is provided at 25 µL, 10mM.
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Eprodisate is a new compound designed to interfere with interactions between amyloidogenic proteins and glycosaminoglycans and thereby inhibit polymerization of amyloid fibrils and deposition of the fibrils in tissues[1]. Eprodisate slow the progression of AA amyloidosis-related renal disease and has possible applicability to other types of amyloidosis[2].
[1]. Dember LM, et al. Eprodisate for the treatment of renal disease in AA amyloidosis. N Engl J Med. 2007 Jun 7;356(23):2349-60. [2]. Manenti L, et al. Eprodisate in amyloid A amyloidosis: a novel therapeutic approach• Expert Opin Pharmacother. 2008 Aug;9(12):2175-80.
Average Rating: 5 (Based on Reviews and 17 reference(s) in Google Scholar.)
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