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M2 ion channel blocker

カタログ番号GC36519

M2 イオン チャネル ブロッカーは、M2 イオン チャネルの活性を阻害および遮断することができます。抗ウイルス剤です。

Products are for research use only. Not for human use. We do not sell to patients.

M2 ion channel blocker 化学構造

Cas No.: 1190215-03-2

サイズ 価格 在庫数 個数
100mg
$167.00
在庫あり

Tel:(909) 407-4943 Email: sales@glpbio.com


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Sample solution is provided at 25 µL, 10mM.

Description of M2 ion channel blocker

M2 ion channel blocker is capable of inhibiting and blocking the activity of M2 ion channel;Antiviral agent.

[1]. Zhang, Wenjuan; Xu, Jing; Liu, Fang. Heterodimers of histidine and amantadine as inhibitors for wild type and mutant M2 channels of influenza A. Chinese Journal of Chemistry (2010), 28(8), 1417-1423.

Chemical Properties of M2 ion channel blocker

Cas No. 1190215-03-2 SDF
Canonical SMILES O=C(OC)[C@H](CC1C=NC=N1)NCC2(C[C@H]3C4)C[C@H]4C[C@H](C3)C2
Formula C18H27N3O2 M.Wt 317.43
溶解度 Water: < 0.1 mg/mL (insoluble) Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of M2 ion channel blocker

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 3.1503 mL 15.7515 mL 31.503 mL
5 mM 0.6301 mL 3.1503 mL 6.3006 mL
10 mM 0.315 mL 1.5752 mL 3.1503 mL
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In vivo Formulation Calculator (Clear solution) of M2 ion channel blocker

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

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Review for M2 ion channel blocker

Average Rating: 5 ★★★★★ (Based on Reviews and 40 reference(s) in Google Scholar.)

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