Mal-PEG2-VCP-Eribulin |
| カタログ番号GC36533 |
Mal-PEG2-VCP-エリブリンは、ADC リンカー (Mal-PEG2-VCP) とエリブリンで構成されています。エリブリンは、機構的にユニークな癌の微小管阻害剤です。 Mal-PEG2-VCP-Eribulin は、抗体結合体用のエリブリンベースの薬剤です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2130869-18-8
Sample solution is provided at 25 µL, 10mM.
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Mal-PEG2-VCP-Eribulin consists the ADCs linker (Mal-PEG2-VCP) and Eribulin[1]. Eribulin is a mechanistically unique microtubule inhibitor for cancer[2]. Mal-PEG2-VCP-Eribulin is an Eribulin-based drug for antibody conjugates[1].
[1]. Earl F Albone, et al. Eribulin-based antibody-drug conjugates and methods of use. US20170252458A1. [2]. Towle MJ, et al. Eribulin induces irreversible mitotic blockade: implications of cell-based pharmacodynamics for in vivo efficacy under intermittent dosing conditions. Cancer Res. 2011 Jan 15;71(2):496-505.
Average Rating: 5 (Based on Reviews and 8 reference(s) in Google Scholar.)
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