Micheliolide |
カタログ番号GC36606 |
ミケリオライドは、ラット メサンギウム細胞 (MC) における高グルコース刺激による NF-κB の活性化、IκBα の分解、および MCP-1、TGF-β1、および FN の発現を効果的に減衰させることができた。
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Cas No.: 68370-47-8
Sample solution is provided at 25 µL, 10mM.
Micheliolide could effectively attenuate the high glucose-stimulated activation of NF-κB, the degradation of IκBα, and the expression of MCP-1, TGF-β1 and FN in rat mesangial cells (MCs).
[1]. Jia QQ, et al. Sesquiterpene lactones and their derivatives inhibit high glucose-induced NF-κB activation and MCP-1 and TGF-β1 expression in rat mesangial cells. Molecules. 2013 Oct 21;18(10):13061-77.
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