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PrPSc-IN-1

カタログ番号GC37019

PrPSc-IN-1 は蛍光プローブで、ミスフォールドタンパク質 PrPSc に結合し、その蓄積を阻害し、IC50 は 1.6 μM です。

Products are for research use only. Not for human use. We do not sell to patients.

PrPSc-IN-1 化学構造

Cas No.: 1315475-30-9

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

PrPSc-IN-1 is a fluorescent probe, binds to the misfolded protein PrPSc, inhibits its accumulation, with an IC50 of 1.6 μM. Anti-prion activity[1]. IC50:1.6 μM (PrPSc)[1]

[1]. Zaccagnini L, et al. Identification of novel fluorescent probes preventing PrPSc replication in prion diseases. Eur J Med Chem. 2017 Feb 15;127:859-873.

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