Teneligliptin hydrobromide hydrate |
| カタログ番号GC37757 |
テネリグリプチン臭化水素酸塩水和物は、強力なケモタイプ プロリルチアゾリジンベースの DPP-4 阻害剤であり、in vitro でヒト血漿、ラット血漿、およびヒト組換え DPP-4 を約 1 nM の IC50 で競合的に阻害します 。
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Cas No.: 1572583-29-9
Sample solution is provided at 25 µL, 10mM.
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Teneligliptin hydrobromide hydrate is a potent chemotype prolylthiazolidine-based DPP-4 inhibitor, which competitively inhibits human plasma, rat plasma, and human recombinant DPP-4 in vitro, with IC50s of approximately 1 nM[1].
[1]. Fukuda-Tsuru S, et al. A novel, potent, and long-lasting dipeptidyl peptidase-4 inhibitor, teneligliptin, improves postprandial hyperglycemia and dyslipidemia after single and repeated administrations. Eur J Pharmacol. 2012 Dec 5;696(1-3):194-202.
Average Rating: 5 (Based on Reviews and 37 reference(s) in Google Scholar.)
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