Nisin Z(≥900IU/mg) |
| カタログ番号GD19056 |
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 137061-46-2
Sample solution is provided at 25 µL, 10mM.
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Nisin Z is an antimicrobial and anti-inflammatory peptide. Nisin Z is effective against Gram-positive bacteria and fungi, such as C. albicans.
Nisin Z (10 μg/mL, 24 h) increases gingival fibroblasts detachment and differentiation[2].
Nisin Z (25-75 μg/mL, 24 h) decreases C. albicans adhesion to the gingival cells[2].
Nisin Z (500 and 1000 μg/mL, 24 h) inhibits germ tube formation by C. albicans[3].
Nisin Z (100 μg/mL, 12 h) reduces the production of LPS-induced pro-inflammatory cytokines (i.e., IL-6, TNF-伪, IL-1β) in MCF10A cells[4].
Nisin Z (10-100 μg/mL, 12 h) inhibits the activation of the ERK1/2 and p38 MAPK signaling pathway in LPS-induced MCF10A cells[4].
Nisin Z (1, 5, and 10 mg/kg, i.p.) prevents the pathological damage in mastitis mouse mode caused by LPS[4].
[1]. Webber JL, et al. Incorporation and antimicrobial activity of nisin Z within carrageenan/chitosan multilayers. Sci Rep. 2021 Jan 18;11(1):1690.
[2]. Akerey B, et al. In vitro efficacy of nisin Z against Candida albicans adhesion and transition following contact with normal human gingival cells. J Appl Microbiol. 2009 Oct;107(4):1298-307.
[3]. Le Lay C, et al. Nisin Z inhibits the growth of Candida albicans and its transition from blastospore to hyphal form. J Appl Microbiol. 2008 Nov;105(5):1630-9.
[4]. Huang F, et al. Nisin Z attenuates lipopolysaccharide-induced mastitis by inhibiting the ERK1/2 and p38 mitogen-activated protein kinase signaling pathways. J Dairy Sci. 2022 Apr;105(4):3530-3543.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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