GDC-2394 |
カタログ番号GC69156 |
GDC-2394は、経口摂取により有効で選択的なNLRP3阻害剤であり、同時にIL-1βも抑制し、IC50は0.4μM(人間IL-1β)および0.1μM(マウスIL-1β)です。GDC-2394はNLRP3誘導のcaspase-1活性を抑制しますが、NLRC4依存性の炎症小体活性化を抑制しません。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2238822-07-4
Sample solution is provided at 25 µL, 10mM.
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Average Rating: 5
(Based on Reviews and 30 reference(s) in Google Scholar.)Review for GDC-2394
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