Ganglioside GM3 |
| カタログ番号GF11251 |
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 124579-05-1
Sample solution is provided at 25 µL, 10mM.
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Ganglioside GM3, produced by addition of sialic acid to LacCer, is expressed mainly in adipose tissue and muscle in humans and mice, and liver and serum in humans. GM3 expression in adipocytes is induced by stimulation of the inflammatory cytokines TNF-伪 and IL-1尾, derived from tissue macrophages[2].
[1]. Nihei W, et al. NPC1L1-dependent intestinal cholesterol absorption requires ganglioside GM3 in membrane microdomains. J Lipid Res. 2018 Nov;59(11):2181-2187.
[2]. Inokuchi JI, et al. Pathophysiological Significance of GM3 Ganglioside Molecular Species With a Particular Attention to the Metabolic Syndrome Focusing on Toll-Like Receptor 4 Binding. Front Mol Biosci. 2022 May 30;9:918346.
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