3'-Azido-3'-deoxyadenosine |
| カタログ番号GF31623 |
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 58699-62-0
Sample solution is provided at 25 µL, 10mM.
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3'-Azido-3'-deoxyadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. 3'-Azido-3'-deoxyadenosine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
Review for 3'-Azido-3'-deoxyadenosine
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Review for 3'-Azido-3'-deoxyadenosine
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