(1R，8S，9s)-Bicyclo[6.1.0]non-4-yn-9-ylmethanol |
| カタログ番号GF53854 |
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![(1R，8S，9s)-Bicyclo[6.1.0]non-4-yn-9-ylmethanol 化学構造](/media/struct/default.png "(1R，8S，9s)-Bicyclo[6.1.0]non-4-yn-9-ylmethanol 化学構造")
Cas No.: 1263166-90-0
Sample solution is provided at 25 µL, 10mM.
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BCN-OH (endo-9-Hydroxymethylbicyclo[6.1.0]non-4-yne) is a mitochondrial probe based on the lyophilic bidentate bicyclic ligand BCN and is a control reagent for BCN-TPP. The TPP group is a reactive sulfenic acid probe that targets mitochondria. BCN-TPP is known to affect mitochondrial energy, causing a sharp decrease in basal respiration, causing it to exhibit faster reaction kinetics with sulfonated proteins. BCN-OH does not contain hydrophobic triphenylphosphonium (TPP) ions. Using BCN-OH as a control allows the TPP group to be safely introduced when designing sulfenic acid traps.
[1]. Li Z, et al. Triphenylphosphonium-Derived Protein Sulfenic Acid Trapping Agents: Synthesis, Reactivity, and Effect on Mitochondrial Function. Chem Res Toxicol. 2019 Mar 18;32(3):526-534.
Review for (1R，8S，9s)-Bicyclo[6.1.0]non-4-yn-9-ylmethanol
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
Review for (1R，8S，9s)-Bicyclo[6.1.0]non-4-yn-9-ylmethanol
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