Gln-AMS TFA |
カタログ番号GC34331 |
Gln-AMS (TFA) は、Ia 型アミノアシル tRNA 合成酵素 (AARS) 阻害剤です。
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Sample solution is provided at 25 µL, 10mM.
Gln-AMS (TFA) is a type Ia aminoacyl-tRNA synthetase (AARS) inhibitor. Gln-AMS inhibits glutaminyl-tRNA synthetase (GlnRS) with a Ki of 1.32 µM.
Gln-AMS (TFA) is a type Ia aminoacyl-tRNA synthetase (AARS) inhibitor[2].
[1]. Rath VL, et al. How glutaminyl-tRNA synthetase selects glutamine. Structure. 1998 Apr 15;6(4):439-49. [2]. Fang P, et al. Structural basis for full-spectrum inhibition of translational functions on a tRNA synthetase. Nat Commun. 2015 Mar 31;6:6402.
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