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Glutaminase C Inhibitor 11

カタログ番号GC91427

グルタミン酸Cインヒビター11は、グルタミン酸C(GAC)の阻害剤です。

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Glutaminase C Inhibitor 11 化学構造

サイズ 価格 在庫数 個数
1mg
$111.00
在庫あり
5mg
$525.00
在庫あり
10mg
$995.00
在庫あり

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
Glutaminase C inhibitor 11 is an inhibitor of glutaminase C (GAC).1 It inhibits GAC enzyme activity (EC50 = 10.64 nM) and reduces the viability of A549 non-small cell lung cancer (NSCLC) cells (IC50 = 4.025 nM). Glutaminase C inhibitor 11 (0.1 and 1 µM) reduces colony formation by, and intracellular glutamate levels in, A549 cells. In vivo, glutaminase C inhibitor 11 (100 mg/kg) reduces tumor growth in an A549 mouse xenograft model.

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