GPX4 24 |
| カタログ番号GC90827 |
GPX4阻害剤
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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GPX4 24 is an inhibitor of glutathione peroxidase 4 (GPX4) and a derivative of (1S,3R)-RSL3 .1 It covalently binds to GPX4 in 4T1 murine mammary carcinoma cells in a concentration-dependent manner. GPX4 24 induces ferroptosis in GPX4-dependent HT-1080 fibrosarcoma cells (EC50 = 0.16 µM). It increases kidney and plasma malondialdede (MDA) levels in mice when administered at a dose of 200 mg/kg.
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Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
Review for GPX4 24
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