H-Gly-Pro-Arg-Pro-OH (acetate) (Synonyms: GPRP) |
カタログ番号GC18983 |
H-Gly-Pro-Arg-Pro-OH (アセテート) (Gly-Pro-Arg-Pro アセテート) は、フィブリノーゲンと血小板膜糖タンパク質 IIb/IIIa 複合体 (GPIIb/IIIa) との相互作用を阻害するフィブリン重合阻害剤です。
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Cas No.: 157009-81-9
Sample solution is provided at 25 µL, 10mM.
H-Gly-Pro-Arg-Pro-OH (GPRP) is a peptide corresponding partly to the amino terminus of the Aα chain and Bβ chain of fibrin. It inhibits the spontaneous polymerization of fibrin monomers and also inhibits ADP-induced platelet aggregation (IC50 = 3 mM). GPRP binds to the fibrinogen D domain, inhibiting the ability of fibrinogen to bind to the platelet membrane glycoprotein GPIIb/IIIa.
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