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H-Phe-OH (Synonyms: NSC 79477, (-)-Phenylalanine)

カタログ番号GA10299

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H-Phe-OH 化学構造

Cas No.: 63-91-2

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100g
$39.00
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500g
$89.00
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Sample solution is provided at 25 µL, 10mM.

Description of H-Phe-OH

L-Phenylalanine is an amino acid, which is widely used in the production of food flavors and pharmaceuticals[1]. L-Phenylalanine binds to the α2δ subunit of voltage-dependent Ca2+ channels, with a Ki value of 980 nM[2].

References:
[1]. Wu WB, et al. Enhancement of l-phenylalanine production in Escherichia coli by heterologous expression of Vitreoscilla hemoglobin. Biotechnol Appl Biochem. 2018 May;65(3):476-483.
[2]. Mortell KH, et al. Structure-activity relationships of alpha-amino acid ligands for the alpha2delta subunit of voltage-gated calcium channels. Bioorg Med Chem Lett. 2006 Mar 1;16(5):1138-41.

Chemical Properties of H-Phe-OH

Cas No. 63-91-2 SDF
同義語 NSC 79477, (-)-Phenylalanine
Chemical Name (2S)-2-amino-3-phenylpropanoic acid
Canonical SMILES C1=CC=C(C=C1)CC(C(=O)O)N
Formula C9H11NO2 M.Wt 165.2
溶解度 Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of H-Phe-OH

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 6.0533 mL 30.2663 mL 60.5327 mL
5 mM 1.2107 mL 6.0533 mL 12.1065 mL
10 mM 0.6053 mL 3.0266 mL 6.0533 mL
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In vivo Formulation Calculator (Clear solution) of H-Phe-OH

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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