Halofantrine hydrochloride (SKF-102886) (Synonyms: (±)-Halofantrine, SKF 102886, WR 171669) |
| カタログ番号GC32377 |
ハロファントリン塩酸塩 (SKF-102886) (SKF-102886) は、ヒト エーテル ア ゴー ゴー関連遺伝子 (HERG) チャネルの阻害と強力な抗マラリア化合物による遅延整流カリウム電流の遮断薬です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 36167-63-2
Sample solution is provided at 25 µL, 10mM.
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Halofantrine hydrochloride (SKF-102886) is a blocker of delayed rectifier potassium current via the inhibition of human-ether-a-go-go-related gene (HERG) channel and a potent antimalarial compound[1][2].
[1]. Krishna S, et al. Pharmacokinetics, efficacy and toxicity of parenteral halofantrine in uncomplicated malaria. Br J Clin Pharmacol. 1993 Dec;36(6):585-91. [2]. Tie, H., et al., Inhibition of HERG potassium channels by the antimalarial agent halofantrine. Br. J. Pharmacol. 130, 1967-1975, (2000) Traebert.
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