ホーム>>Signaling Pathways>> DNA Damage/DNA Repair>> HDAC>>HDAC8-IN-1

HDAC8-IN-1 (Synonyms: MDK-7933)

カタログ番号GC19189

HDAC8-IN-1 は、IC50 が 27.2 nM の HDAC8 阻害剤です。

Products are for research use only. Not for human use. We do not sell to patients.

HDAC8-IN-1 化学構造

Cas No.: 1417997-93-3

サイズ 価格 在庫数 個数
5mg
$80.00
在庫あり
10mg
$121.00
在庫あり
25mg
$241.00
在庫あり
50mg
$369.00
在庫あり
100mg
$637.00
在庫あり

Tel:(909) 407-4943 Email: sales@glpbio.com


顧客レビュー

カスタマーレビューに基づきます。

  • GlpBio Citations

    GlpBio Citations
  • Bioactive Compounds Premium Provider

    Bioactive Compounds Premium Provider

Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

HDAC8-IN-1 is a HDAC8 inhibitor with an IC50 of 27.2 nM.

HDAC8-IN-1 is a HDAC8 inhibitor with an IC50 of 27.2 nM in cancer cell lines. HDAC8-IN-1 (compound 22 d) shows antiproliferative effects toward several human lung cancer cell lines (A549, H1299, and CL1-5); HDAC8-IN-1 exhibits cytotoxicity against human lung CL1-5 cells without significant cytotoxicity for normal IMR-90 cells[1].

References:
[1]. Huang WJ, et al. Synthesis and biological evaluation of ortho-aryl N-hydroxycinnamides as potent histone deacetylase (HDAC) 8 isoform-selective inhibitors. ChemMedChem. 2012 Oct;7(10):1815-24.

レビュー

Review for HDAC8-IN-1

Average Rating: 5 ★★★★★ (Based on Reviews and 32 reference(s) in Google Scholar.)

5 Star
100%
4 Star
0%
3 Star
0%
2 Star
0%
1 Star
0%
Review for HDAC8-IN-1

GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.

Required fields are marked with *

You may receive emails regarding this submission. Any emails will include the ability to opt-out of future communications.