Hepln-13 |
| カタログ番号GC62265 |
Hepln-13 は、IC50 が 0.33 μM の強力な経口活性ヘプシン阻害剤です。 Hepln-13 は、転移性前立腺癌の研究に使用できます。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 64369-13-7
Sample solution is provided at 25 µL, 10mM.
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Hepln-13 is a potent and orally active Hepsin inhibitor with an IC50 of 0.33 µM. Hepln-13 can be used for the research of metastatic prostate cancer[1].
Hepln-13 (10 µM; 2 hours; 293 cells) inhibits cleavage[1].
HepIn-13 displays dose dependent inhibition of Hepsin overexpression-relevant prostate cancer phenotypes and blocks prostate cancer metastasis[1].
[1]. Tang X, et al. Targeted inhibition of cell-surface serine protease Hepsin blocks prostate cancer bone metastasis. Oncotarget. 2014;5(5):1352-1362.
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