IRAK4-IN-20 |
| カタログ番号GC71135 |
IRAK4-IN-20（化合物BAY-138845）は経口活性IRAK 4阻害剤であり、IC 50は3.55 nMである。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1931994-80-7
Sample solution is provided at 25 µL, 10mM.
;)
,-1-7$$$37316672.jpg');)
;)
;)
$$$36806353.jpg');)
;33(7)%EF%BC%9A546-561$$$37156877.jpg');)
;)
;)
;)
%201124-1138.$$$35908550.jpg');)
%20766-780.$$$37100057.jpg');)
%20418-432.$$$36893736.jpg');)
%EF%BC%9A-240-255.$$$35108512.jpg');)
533-545$$$36543525.jpg');)
%201-13.$$$36600053.jpg');)
;)
IRAK4-IN-20 (Compound BAY-1834845) (500 nM, 20 h) decreases inflammatory cytokines secretion effectively in an in vitro treatment of LPS stimulated human peripheral blood mononuclear cells (PBMC)[1].
IRAK4-IN-20 (Compound BAY-1834845) (150 mg/kg; p.o.; once or twice) effectively prevents acute respiratory distress syndrome in mice[1].
References:
[1]. Li Q, et al. Oral IRAK4 Inhibitor BAY-1834845 Prevents Acute Respiratory Distress Syndrome. Biomedicine & Pharmacotherapy, 2022: 113459.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *