Isotanshinone IIA |
| カタログ番号GC33791 |
アビエタン型ジテルペン代謝産物であるイソタンシノン IIA は、プロテイン チロシン ホスファターゼ 1B (PTP1B) 活性を IC50 0f 11.4 μM で非競合的に阻害することができた。
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Cas No.: 20958-15-0
Sample solution is provided at 25 µL, 10mM.
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Isotanshinone IIA, an abietane-type diterpene metabolite, could non-competitively inhibit Protein Tyrosine Phosphatase 1B (PTP1B) activity with an IC50 0f 11.4 μM.
[1]. Han YM, et al. PTP1B inhibitory effect of abietane diterpenes isolated from Salvia miltiorrhiza. Biol Pharm Bull. 2005 Sep;28(9):1795-7.
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