Iturin A-2 |
| カタログ番号GC91049 |
多様な生物学的活性を持つ環状リポペプチド
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 83785-07-3
Sample solution is provided at 25 µL, 10mM.
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Iturin A-2 is a cyclic lipopeptide that has been found in B. subtilis and has diverse biological activities.1,2,3,4 It is active against the plant pathogenic fungus P. expansum (MIC = 8 µg/disk).1 Iturin A-2 induces cytotoxicity in MCF-7 and BT474 breast cancer and HeLa cervical cancer cells (IC50s = 66.81, 95.04, and 77.5 µg/ml, respectively).2 It reduces southern corn leaf blight lesion area induced by B. maydis in greenhouse studies when applied at concentrations of 100 and 300 mg/kg AI and reduces the incidence of southern corn leaf blight in field studies at 300 and 500 mg/kg AI.3 Iturin A-2 (12.5 µg/ml) inhibits cell division, but not nuclear division, in isolated fertilized starfish eggs.4
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