J27644 |
| カタログ番号GC91389 |
J27644は、ヒストンデアセチラーゼ6（HDAC6; IC50 = 10 nM）の阻害剤です。
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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J27644 is an inhibitor of histone deacetylase 6 (HDAC6; IC50 = 10 nM).1 It is selective for HDAC6 over HDAC1-5 (IC50s = 211-516 nM) and HDAC7, -8, -9, and -11 (IC50s = 137-812 nM). J27644 (10 µM) reduces the level of proteins involved in fibrosis, including collagen 1A1, α-smooth muscle actin (α-SMA), and fibronectin, in human pulmonary fibroblasts in vitro.
Review for J27644
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
Review for J27644
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