JAK1-IN-13 |
| カタログ番号GC71475 |
JAK1-IN-13(化合物36b)は、jak1のic50が0.044 nmであることを示す、経口での強力かつ高選択的な阻害剤である。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2778330-90-6
Sample solution is provided at 25 µL, 10mM.
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JAK1-IN-13 (compound 36b) is an orally active, potent and highly selective inhibitor of JAK1 with an IC50 of 0.044 nM. JAK1-IN-13 significantly decreases STAT3 phosphorylation.
References:
[1]. Park E, et al. Identification and Biological Evaluation of a Potent and Selective JAK1 Inhibitor for the Treatment of Pulmonary Fibrosis. J Med Chem. 2023 Dec 14;66(23):16342-16363.
Review for JAK1-IN-13
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
Review for JAK1-IN-13
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