KPH2f |
| カタログ番号GC70894 |
KPH2fは安全、積極的に砥石IC50sと効率的な二重URAT1 / GLUT9拮抗薬0.24μM・9.37μM URAT1とGLUT9。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2760615-09-4
Sample solution is provided at 25 µL, 10mM.
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KPH2f is a safe, orally active, and effective dual URAT1/GLUT9 inhibitor with IC50s of 0.24 μM and 9.37 μM for URAT1 and GLUT9, respectively. KPH2f shows little effects on OAT1 and ABCG2 (IC50=32.14 and 26.74 μM).
References:
[1]. Zhao Z, et al. Discovery of novel verinurad analogs as dual inhibitors of URAT1 and GLUT9 with improved Druggability for the treatment of hyperuricemia. Eur J Med Chem. 2022;229:114092.
Review for KPH2f
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
Review for KPH2f
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