KSL-128114 (trifluoroacetate salt) |
| カタログ番号GC90566 |
ペプチドシンテニン阻害剤
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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KSL-128114 is a peptide inhibitor of the membrane regulator syntenin (Ki = 300 nM).1 It reduces the percent viability of A2058 melanoma and patient-derived glioblastoma multiforme (GBM) cells in a concentration-dependent manner. KSL-128114 (50 µM) increases animal survival time in a patient-derived xenograft (PDX) mouse model of GBM using patient-derived GBM cells cultured with KSL-128114 prior to intracranial implantation.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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