Kushenol E |
| カタログ番号GC64060 |
Kushenol E は Sophora flavescens から分離されたフラボノイドのクラスであり、7.7 μM の IC50 と 9.5 μM の Ki を持つ非競合的なインドールアミン 2,3-ジオキシゲナーゼ 1 (IDO1) 阻害剤であり、抗腫瘍活性があります。
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Cas No.: 99119-72-9
Sample solution is provided at 25 µL, 10mM.
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Kushenol E is a class of flavonoids isolated from Sophora flavescens and is a non-competitive indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor with an IC50 of 7.7 µM and a Ki of 9.5 µM, has anti-tumor activity[1].
[1]. Kwon M, et al. Inhibitory effects of flavonoids isolated from Sophora flavescens on indoleamine 2,3-dioxygenase 1 activity. J Enzyme Inhib Med Chem. 2019 Dec;34(1):1481-1488.
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