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Labetalol HCl (Synonyms: AH 5158A, NSC 290312, SCH 15719W)

カタログ番号GC10887

ラベタロール HCl は、高血圧の治療に使用される混合アルファ/ベータ アドレナリン拮抗薬です。

Products are for research use only. Not for human use. We do not sell to patients.

Labetalol HCl 化学構造

Cas No.: 32780-64-6

サイズ 価格 在庫数 個数
100mg
$14.00
在庫あり
10mM (in 1mL DMSO)
$15.00
在庫あり
500mg
$35.00
在庫あり

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Sample solution is provided at 25 µL, 10mM.

Description of Labetalol HCl

Labetalol hydrochloride is a mixed alpha/beta adrenergic antagonist that is used to treat high blood pressure.

Chemical Properties of Labetalol HCl

Cas No. 32780-64-6 SDF
同義語 AH 5158A, NSC 290312, SCH 15719W
Chemical Name 2-hydroxy-5-[1-hydroxy-2-(4-phenylbutan-2-ylamino)ethyl]benzamide;hydrochloride
Canonical SMILES CC(CCC1=CC=CC=C1)NCC(C2=CC(=C(C=C2)O)C(=O)N)O.Cl
Formula C19H25ClN2O3 M.Wt 364.87
溶解度 ≥ 18.24mg/mL in DMSO Storage 4°C, protect from light
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Labetalol HCl

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.7407 mL 13.7035 mL 27.407 mL
5 mM 0.5481 mL 2.7407 mL 5.4814 mL
10 mM 0.2741 mL 1.3704 mL 2.7407 mL
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計算

In vivo Formulation Calculator (Clear solution) of Labetalol HCl

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

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Average Rating: 5 ★★★★★ (Based on Reviews and 24 reference(s) in Google Scholar.)

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